英文名称
HMGB1 Rabbit pAb
中文名称
高迁移率族蛋白B1抗体
英文别名
High mobility group protein B1; Amphoterin; High mobility group 1; High Mobility Group Box 1; High mobility group protein 1; HMG3; HMGB 1; HMGB-1; Hmgb1 protein; Nonhistone chromosomal protein HMG1; SBP 1; SBP-1; Sulfoglucuronyl carbohydrate binding protein; HMGB1_HUMAN.
产品应用
Flow-Cyt=1μg/Test
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
交叉反应
Human, Mouse, Rat (predicted: Cow)
抗体来源
Rabbit
免疫原
KLH conjugated synthetic peptide derived from human HMGB1: 75-170/215
亚型
IgG
性状
Liquid
纯化方法
affinity purified by Protein A
克隆类型
Polyclonal
理论分子量
25 kDa
浓度
1mg/ml
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域
Epigenetics and Nuclear Signaling > Histones > HMGs
Epigenetics and Nuclear Signaling > Transcription > Domain Families > HMG Box
Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > SARS Coronavirus
Signal Transduction > Antibodies > hmgb1
亚基
Component of the RAG complex composed of core components RAG1 and RAG2, and associated component HMGB1 or HMGB2.
亚细胞定位
Nucleus. Chromosome.
相似性
Belongs to the HMGB family.
Contains 2 HMG box DNA-binding domains.
SWISS
P09429
Gene ID
3146
功能
DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells.
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
数据库链接
Entrez Gene : 282691 Cow
Entrez Gene : 3146 Human
Entrez Gene : 100862258 Mouse
Entrez Gene : 15289 Mouse
Entrez Gene : 25459 Rat
Omim : 163905 Human
SwissProt : P10103 Cow
SwissProt : P09429 Human
